Instituto Mixto Universitario de Deporte y Salud

PTS -Parque Tecnológico de la Salud.
C/. Menéndez Pelayo 32,
18016 Granada. España

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Francisco J. Amaro Gahete PROFITH

Francisco Amaro Gahete

Associated Professor

Email: amarof@ugr.es

Francisco J. Amaro Gahete (FAG) holds a Bachelor’s degree in Physical Activity and Sport Sciences (2009-2013) and a Medical degree (2016-2022) from the University of Granada. FAG completed his Doctoral studies in Biomedicine in 2019 (Cum Laude) with an Extraordinary Doctoral Award (https://n9.cl/m82c0) and the “PhD Academy Award” conferred by the top-ranked JCR journal in Sports Medicine (British Journal of Sport Medicine – https://n9.cl/h3jd2).

After completing various international research stays (e.g., at the University of Copenhagen) and teaching engagements at the Camilo José Cela University, FAG obtained a position of Associate Professor at the Faculty of Medicine (University of Granada).

His most significant lines of research encompass:

– Physical exercise and energy metabolism.

– Physical exercise and cardiovascular health.

– Emerging training trends: impact on health and performance.

– Anti-aging: lifestyle-related strategies.

– Chronobiology and circadian rhythms: impact of physical exercise and nutrition.

– Exercise, nutrition, and psychology in oncological patients.

– Virtual reality in stroke patients.

Top-5 publications

  1. Amaro-Gahete FJ*. Exercise training increases levels of the anti-ageing Klotho protein: health-related cardiometabolic implications. The FIT-AGEING randomised controlled trial. British Journal of Sport Medicine, 2021: 1.https://doi.org/10.1136/bjsports-2020-102120

Contribution: In this article (awarded by the BJSM journal, top-ranked in Sport Sciences JCR), the main findings of FAG’s doctoral thesis are summarized, demonstrating that physical exercise, especially when performed at high intensity, improves various biomarkers of aging, cardiovascular health, and metabolic health.

  1. Amaro‐Gahete FJ*, De-la-O A, Jurado-Fasoli, Sanchez-Delgado G, Ruiz JR, Castillo M. Metabolic rate in sedentary adults, following different exercise training interventions: THE FIT-AGEING randomized controlled trial. Clinical Nutrition, 2020: 39 (11): 3230-3240.https://doi.org/10.1016/j.clnu.2020.02.001

Contribution: In this study, we highlight that concurrent and high-intensity physical exercise improves fat oxidation at rest and during exercise, as well as metabolic rate in healthy middle-aged adults, findings with high scientific and clinical potential in the context of chronic cardio-metabolic pathologies.

  1. Amaro-Gahete FJ*, Sanchez-Delgado G, Ara, I, Ruiz JR. Cardiorespiratory fitness may influence metabolic inflexibility during exercise in obese persons. J Clin End & Met, 2019: 104 (12): 5780-5790.https://doi.org/10.1210/jc.2019-01225

Contribution: In this study, we demonstrate that individuals with obesity exhibit metabolic inflexibility during physical exercise, suggesting that an improvement in fitness induced by an exercise program could alleviate the metabolic inflexibility status in patients with this pathology.

  1. Carneiro-Barrera A, Amaro-Gahete FJ, Guillén-Riquelme A, Jurado-Fasoli L, Sáez-Roca G, Martín-Carrasco C, Buela-Casal G & Ruiz JR (2022). Effect of an Interdisciplinary Weight Loss and Lifestyle Intervention on Obstructive Sleep Apnea Severity: The INTERAPNEA Randomized Clinical Trial. JAMA Network Open, 5(4): e3228212.https://doi.org/10.1001/jamanetworkopen.2022.8212

Contribution: This study highlights for the first time that obstructive sleep apnea is not a chronic disease and that it can potentially be curable through lifestyle changes enabling weight reduction. Specifically, within just 8 weeks of intervention, we succeeded in discontinuing CPAP therapy in 50% of patients who underwent a multidisciplinary program based on exercise, nutrition, and psychological support.

  1. Chavez-Guevara, IA, Amaro-Gahete, FJ, Ramos-Jimenez, A, & Brun, JF. (2023). Toward exercise guidelines for optimizing fat oxidation during exercise in obesity: A systematic review and meta-regression. Sports Medicine, 53(12), 2399-2416.https://doi.org/10.1007/s40279-023-01897-y

Contribution: This systematic review and meta-regression emphasize the importance of heart rate as a precise indicator for establishing the optimal exercise intensity and elucidate the biological and methodological factors influencing the estimation of maximal fat oxidation during exercise.