Instituto Mixto Universitario de Deporte y Salud

PTS -Parque Tecnológico de la Salud.
C/. Menéndez Pelayo 32,
18016 Granada. España

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Luis Gracia Marco PROFITH

Luis Gracia Marco

Associated Professor

Email: lgracia@ugr.es

Luis Gracia Marco works as Associate Professor at the University of Granada (Spain). He joined the university in 2017 as postdoc researcher within the “Talent Identification Programme – UGR Fellows”, at the Faculty of Sport Sciences. Previously, he worked as Senior Lecturer within the Sport and Health Sciences Department at the University of Exeter (UK). Luis holds a BSc in Physical Education teaching (University of Zaragoza, Spain), a BSc in Sport and Health Sciences (University of Lleida, Spain) and an international PhD in Sports Medicine (University of Zaragoza, Spain). He has obtained recent grants as Principal Investigator in highly competitive international grants, such as Marie Skłodowska-Curie (funded by the European Commission), La Caixa Foundation and Ministerio de Ciencia e Innovación. Currently, he is leading a research line in exercise oncology.

Luis´research is focused on understanding how exercise may benefit bone development. He is currently leading the research line “Exercise and Bone” in PROFITH.

His main research interests are Physical activity and body composition, exercise and bone health, exercise and cancer,assessment of physiological fragility.

 

Top-5 publications

  1. Vlachopoulos D, Barker AR, Ubago-Guisado E, Fatouros IG, Knapp KM, Williams CA, Gracia-Marco L. Longitudinal Adaptations of Bone Mass, Geometry, and Metabolism in Adolescent Male Athletes: The PRO-BONE Study. J Bone Miner Res. 2017 Nov;32(11):2269-2277. doi: 10.1002/jbmr.3206. Epub 2017 Aug 1. PMID: 28685886.https://doi.org/10.1002/jbmr.3206

Contribution: Principal investigator. In this study, with a longitudinal design, we evaluated the impact of 1 year of regular sports practice of very common sports on the health and geometry of the bones of the hip and lumbar spine, closely linked to the diagnosis of osteoporosis in adulthood. The findings had very important implications for obtaining a high peak bone mass in order to contribute to the prevention of bone diseases at older ages. 

  1. Vlachopoulos D, Barker AR, Ubago-Guisado E, Williams CA, Gracia-Marco L. A 9-Month Jumping Intervention to Improve Bone Geometry in Adolescent Male Athletes. Med Sci Sports Exerc. 2018 Dec;50(12):2544-2554. doi: 10.1249/MSS.0000000000001719. PMID: 30067592.https://doi.org/10.1249/mss.0000000000001719

Contribution: Principal Investigator. Randomized controlled trial using a 9-month physical exercise intervention. We observed how athletes who regularly practiced low-impact sports, such as swimming and cycling, saw significant improvements in their bone mass. These results were very relevant and allowed us to carry out a transfer to sports clubs, especially low-impact sports (swimming and cycling) in order to include certain exercises based on jumps/impact in their training and promote adequate bone development during adolescence.

  1. Martínez-Vizcaíno V, Cavero-Redondo I, Reina-Gutiérrez S, Gracia-Marco L, Gil-Cosano JJ, Bizzozero-Peroni B, Rodriguez-Artalejo F, Ubago-Guisado E. Comparative effects of different types of exercise on health-related quality of life during and after active cancer treatment: A systematic review and network meta-analysis. J Sport Health Sci. 2023 Nov;12(6):726-738. doi: 10.1016/j.jshs.2023.01.002. Epub 2023 Feb 3. PMID: 36736726; PMCID: PMC10658325.https://doi.org/10.1016/j.jshs.2023.01.002

Contribution: This work includes 85 randomized controlled trials involving almost 7,000 people with cancer with the aim of synthesizing evidence from intervention studies to evaluate the effect of different types of exercise on health-related quality of life during and after cancer treatment. cancer.

  1. Marmol-Perez A, Gil-Cosano JJ, Ubago-Guisado E, Llorente-Cantarero FJ, Pascual-Gázquez JF, Ness KK, Martinez-Vizcaino V, Ruiz JR, Gracia-Marco L. Muscle strength deficits are associated with low bone mineral density in young pediatric cancer survivors: The iBoneFIT project. J Sport Health Sci. 2024 Jan 12:S2095-2546(24)00003-6. doi: 10.1016/j.jshs.2024.01.003. Epub ahead of print. PMID: 38219958.https://doi.org/10.1016/j.jshs.2024.01.003

Contribution: Principal Investigator. This study identified muscle strength deficits and associations of such deficits with lower bone mineral density in a sample of young pediatric cancer survivors. These findings show the importance of incorporating physical exercise plans in cancer survivors.

  1. Marmol-Perez A, Migueles JH, Ubago-Guisado E, Gil-Cosano JJ, Rodriguez-Solana A, Redondo-Tébar A, Llorente-Cantarero FJ, Labayen I, Ortega FB, Ruiz JR, Gracia-Marco L. Every Move Counts to Improve Bone Health at Clinical Sites in Young Pediatric Cancer Survivors: The iBoneFIT Project. Med Sci Sports Exerc. 2024 Jan 31. doi: 10.1249/MSS.0000000000003397. Epub ahead of print. PMID: 38306313.https://doi.org/10.1249/mss.0000000000003397

Contribution: Principal Investigator. This study uses compositional data analysis to show that any physical activity, even of low intensity, can be important in accelerating the bone regeneration process after childhood cancer.